Sunday, 16 October 2016

Lidocaine Synthesis

Synthesizing this compound was actually really tricky. It looks simply on paper but finding a way to have all three benzene substituents be right next to one another was a challenge.

I learned about Lidocaine in my Neurobiology course. It's an anesthetic that blocks the influx of sodium cations through the membrane of nerve cells. If less sodium cations enter the nerve cells, the interior can't depolarize as much, and there less action potentials are fired.


Check my complete synthesis in the image below:

1 comment:

  1. One of cousin was having trouble with the same topic. I m definitely going to recommend this blog post to her. I might be helpful to her.

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